X-chromosome variants help explain autism’s sex bias

A male is more likely to have autism (and a few other “neurodivergences”) than females. There is now a genetic explanation for at least part of this bias.

One possible explanation is that boys, who typically have only one X chromosome, cannot compensate for an altered copy of an X-chromosome gene in the same way that girls, who have two X chromosomes, can.

This might also kinda explain why females with autism often seem less autistic than males with autism… the XX chromosomes can compensate for the issue more effectively than the XY chromosomes.